Antibacterial, antifungal and anthelmintic activities of root barks of Uvaria hookeri and Uvaria narum.
نویسندگان
چکیده
On a pharmacological screening, substantial antibacterial, antifungal and anthelmintic activities were observed for the hexane and ethyl acetate extracts of the root barks of Uvaria narum Wall. and Uvaria hookeri King. Chromatographic fractionation of these extracts led to the isolation of the triterpenes glutinol, glutinone, taraxerol, beta-sitosterol and Annonaceous acetogenins uvariamicins-I, II and III mixture, isodesacetyluvaricin, squamocin-28-one, narumicins-I and II stereoisomeric mixture, squamocin and panalicin. The acetogenins exhibited antimicrobial and anthelmintic activities in their individual screening comparable with standard drugs and hence their presence could be attributed to a great extent for the biocidal properties of U. narum and U. hookeri extracts.
منابع مشابه
Antidiabetic and hypolipidemic activities of hydroethanolic root extract of Uvaria chamae in streptozotocin induced diabetic albino rats
BACKGROUND Diabetes mellitus is a metabolic disorder of multiple aetiology characterised by hyperglycemia resulting from defects in insulin secretion, insulin action or both. It is a global epidemic ravaging both developed and developing countries. The situation will worsen if nothing is done urgently. In fact, the need to identify natural products with antidiabetic potentials is of great impor...
متن کاملCytotoxic C-benzylated dihydrochalcones from Uvaria acuminata.
Two new C-benzylated dihydrochalcones, isochamuvaritin (1) and acumitin (2), have been isolated from the African medicinal plant Uvaria acuminata, together with the previously reported benzylbenzoate (3), uvaretin (4), isouvaretin (5), diuvaretin (6), and uvangoletin (7). The structural elucidation of compounds 1 and 2 in spectroscopic studies is described. C-Benzylated dihydrochalcones, especi...
متن کاملPhytochemical screening and effect of ethanolic root extract of Uvaria chamae on albino rats in Akwa Ibom State, Nigeria
Phytochemical screening and effect of ethanolic root extract of parameters on albino rats in Akwa Ibom State was investigated. were: haemoglobin concentration (Hb.), white blood cell count (WBC), red blood cell count (RBC), packed cell volume (PCV), platelet (PLT), haemoglobin (MCH), mean corpuscular haemoglobin concentration (MCHC). of the extracts were examined intraperitoneally using albino ...
متن کاملRevision of the African genus Uvariastrum (Annonaceae)
The genus Uvariastrum (Annonaceae) is restricted to continental Africa and is characterized by sepals with folded margins, few carpels and numerous stamens. The genus is mainly found in the tropical lowland rain forests of Africa, with one species growing in a drier woodland habitat. The species name Uvariastrum pynaertii De Wild is reduced into synonymy with Uvariastrum zenkeri Engl. & Diels. ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Journal of ethnopharmacology
دوره 40 3 شماره
صفحات -
تاریخ انتشار 1993